Calcium-D-Glucarate

Verifiable Science

Researchers at the University of Texas M.D. Anderson Cancer Center, Memorial Sloan-Kettering Cancer Center of New York, AMC Cancer Center in Colorado and Ohio State University have extensively studied D-glucarate. Calcium-D-Glucarate^™ a patented form of glucaric acid, is a nutrient with the potential to support healthy detoxification and cellular function.¹ In the gut and liver, phase II detoxification includes an enzymatic process called glucuronidation, in which toxic compounds are bound to glucuronic acids so that they can be eliminated in a safe form from the body via the bile and/or urine.² Beta-glucuronidase is a naturally occurring enzyme found in various organs and cells, which can cleave apart these neutral compounds.³ D-Glucarate has been shown to help modulate beta-glucuronidase enzyme activity, helping the glucuronide conjugates stay intact, so that they can leave the body.⁴ D-glucarate may also help to maintain healthy cell structure and function.⁵ An animal study suggests the promising role of D-glucarate in supporting healthy lipid metabolism.